Figure 2
GO analysis identifies nervous system development and response to stress as the processes with the greatest number of DEG that were higher or lower in PVEC vs. ABEC. (a) Gene Ontology (GO) analysis using the Metacore from Clarivate Analytics identified the top 5 most enriched biological process when separated by higher (red) or lower (blue) differentially expressed genes (DEG) in PVEC vs. ABEC. (b) The top 10 more enriched biological processes when all DEG were analyzed together closely resembles the analysis performed using DEG that were higher in PVEC vs. ABEC. Numbers inside the bars correspond to the number of DEG in each given GO biological process. (c) Canonical pathway enrichment analysis using the Metacore identified the top 10 most enriched pathways in PVEC vs. ABEC, here depicted as grey bars. Numbers inside the bars correspond to the number of DEG that were identified in each given pathway. (d) Canonical pathway enrichment using the Metacore, following partitioning of our data into genes that were higher (red) or lower (blue) in PVEC vs. ABEC identified the top 10 pathways in each category.
