Table 3 Oxidative stress markers and antioxidants in the ASD and TD groups.

From: Simultaneous evaluation of antioxidative serum profiles facilitates the diagnostic screening of autism spectrum disorder in under-6-year-old children

Markers

Total

6 years old and under

ASD

TD

P

ASD

TD

P

Mean (95% CI)

Mean (95% CI)

Mean (95% CI)

Mean (95% CI)

CoQ10 Oxidation Rate (%)

5.2 (4.5–5.9)

4.2 (3.7–4.6)

0.012

3.5 (2.7–4.2)

2.8 (2.4–3.1)

0.244

Total CoQ10 (nmol/L)

829 (714–944)

802 (750–854)

0.552

937 (722–1151)

806 (703–910)

0.727

8-OHdG (pg/mL)

5.9 (5.6–6.2)

6.3 (5.8–6.8)

0.300

6.3 (5.8–6.8)

5.2 (4.4–6.0)

0.001

α-tocopherol (μg/dL)

762 (702–822)

744 (707–781)

0.967

878 (790–996)

780 (707–853)

0.119

Adiponectin (μg/mL)

14.8 (11.7–17.9)

14.6 (13.2–16.1)

0.398

19.8 (14.7–25.0)

15.5 (13.8–17.1)

0.156

Markers

Male

Male 6 years old and under

ASD

TD

P

ASD

TD

P

Mean (95% CI)

Mean (95% CI)

Mean (95% CI)

Mean (95% CI)

CoQ10 Oxidation Rate (%)

5.5 (4.8–6.2)

4.1 (3.4–4.7)

0.004

3.3 (2.3–4.2)

3.0 (2.4–3.6)

0.952

Total CoQ10 (nmol/L)

827 (711–942)

830 (753–906)

0.370

1003 (713–1293)

800 (659–941)

0.571

8-OHdG (pg/mL)

5.9 (5.5–6.2)

6.2 (5.5–6.9)

0.494

6.1 (5.5–6.7)

5.1 (4.2–6.0)

0.011

α-tocopherol (μg/dL)

730 (674–785)

742 (691–793)

0.594

857 (761–953)

774 (678–870)

0.174

Adiponectin (μg/mL)

13.9 (10.6–17.1)

13.9 (12.1–15.6)

0.129

22.3 (15.7–28.9)

14.9 (12.7–17.0)

0.030

  1. ASD autism spectrum disorder, TD typical development, CI confidence interval, CoQ10 coenzyme Q10, 8-OHdG 8-hydroxy-2′-deoxyguanosine.
Back to article page