Figure 2 | Scientific Reports

Figure 2

From: Longitudinal proteomic profiling reveals increased early inflammation and sustained apoptosis proteins in severe COVID-19

Figure 2

Early disease stage inflammation markers in COVID-19 patients. Inflammatory markers activated at the early stage of the disease and their subsequent decline. (A1–J2) Group-wise comparisons of at the early stage of the diseases (up to first 3 days) OLINK NPX values (1) and scatterplots (2) where x-axis denotes time in days from the start of the symptoms, y-axis corresponds to OLINK assay’s measurement’s level and the group specific lines are calculated via loess regression. As the early stage samples were not possible to get from all patients, the number of patients studied in box plots is smaller than in scatter plots. (K) The difference in OLINK NPX levels between the first and the last measurement of each individual, the proteins on y-axis are sorted by the average difference between ICU and non-ICU groups in descending order. (L) PCA plot calculated based on 10 early stage markers.

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