Figure 3

Consistently increased markers of apoptosis and tissue-inflammation in COVID-19 patients. Examples of 10 proteins, including markers associated with apoptotic mechanisms, with increased levels in ICU patients over the disease course. (A1–J2) PEA profiling NPX values per individual (1) and scatterplots (2) where x-axis denotes time in days since the start of the symptoms, y-axis corresponds to the measurement’s level and the group specific lines are calculated via loess regression. (K) PCA plot calculated based on 10 markers' average levels consistently upregulated in COVID-19.