Table 1 Baseline characteristics of patients with and without symptomatic intracranial hemorrhage (sICH) after tPA.
From: Artificial neural network based prediction of postthrombolysis intracerebral hemorrhage and death
| Â | sICH | Non-sICH | p-value |
|---|---|---|---|
n | 25 | 306 | Â |
Age | 68.1 ± 11.0 | 69.2 ± 12.3 | 0.62 |
Female, n (%) | 14 (56) | 119 (38.9) | 0.09 |
Onset-to-hospital time, minutes | 49.8 ± 36.2 | 61.0 ± 44.9 | 0.16 |
Onset-to-treatment time, minutes | 118.0 ± 45.9 | 122.5 ± 45.3 | 0.64 |
BMI, kg/m2 | 24.7 ± 5.0 | 24.9 ± 4.0 | 0.87 |
tPA total dose, mg | 54.6 ± 15.2 | 55.9 ± 13.8 | 0.71 |
Glasgow coma scale score | 11.6 ± 4.2 | 11.8 ± 4.5 | 0.88 |
Systolic BP (mmHg) | 163.9 ± 22.2 | 160.1 ± 29.9 | 0.45 |
Diastolic BP (mmHg) | 100.5 ± 14.7 | 90.4 ± 19.2 | 0.004* |
Baseline NIHSS | 14.0 ± 5.7 | 12.4 ± 6.4 | 0.20 |
Stroke subtype, n (%) | |||
Cardioembolism | 8 (33.3) | 58 (22.0) | 0.046* |
Large-artery atherosclerosis | 10 (41.7) | 108 (40.9) | |
Small-vessel occlusion | 1 (4.2) | 71 (26.9) | |
Others | 5 (20.8) | 27 (10.2) | |
Risk factors, n (%) | |||
Hypertension | 22 (88) | 219 (72.8) | 0.10 |
Diabetes mellitus | 10 (40) | 95 (31.6) | 0.39 |
Hyperlipidemia | 3 (12) | 92 (30.6) | 0.05* |
Atrial fibrillation | 15 (60) | 82 (27.4) | 0.001* |
Previous stroke or TIA | 5 (20) | 55 (18.3) | 0.83 |
Heart disease | 16 (66.7) | 90 (31.4) | 0.0005* |
Smoking | 3 (12) | 63 (20.9) | 0.29 |
Laboratory data | |||
Glucose at admission (mg/dL) | 155.0 ± 55.5 | 154.2 ± 65.0 | 0.95 |
Glucose, fasting (mg/dL) | 149.0 ± 71.1 | 132.0 ± 46.3 | 0.27 |
Creatinine (mg/dL) | 1.1 ± 0.7 | 1.2 ± 1.1 | 0.54 |
Cholesterol (mg/dL) | 174.0 ± 42.3 | 187.5 ± 42.9 | 0.14 |
Triglyceride (mg/dL) | 112.5 ± 65.0 | 127.0 ± 89.8 | 0.32 |
LDL (mg/dL) | 100.1 ± 30.2 | 114.2 ± 36.0 | 0.035* |
HbA1c (%) | 6.4 ± 1.3 | 6.4 ± 1.4 | 0.93 |
Outcome measures | |||
In-hospital death n (%) | 2 (8) | 15 (4.9) | 0.53 |
Death at 3-month, n (%) | 6 (25) | 25 (9.5) | 0.02* |
3-month mRS | 4.2 ± 1.6 | 2.4 ± 1.9 |  < 0.0001* |
