Figure 3

(a) The a-wave and the b-wave of the dark-adapted electroretinogram represent the functional status of the retinal photoreceptors and of their second-order neurons, including bipolar and horizontal cells, respectively. (b) The relationship between the amplitudes of the b-wave and the a-wave obtained from experimental eyes treated with oligomeric Aβ42 (left panel), fibrillar Aβ42 (middle panel) and fibrillar Aβ40 (right panel) are illustrated for each recording session after the injection.