Figure 8
MST illustrating the evolutionary relationships among M. bovis isolates (n = 487) based on combined spoligotyping and 8-loci MIRU-VNTR data, using single locus variant analysis. Circle size is proportional to the number of isolates within each group; nodes are colored by host species (red for cattle (C), green for red deer (RD) and blue for wild boar (WB)); and the different clonal complexes are identified by different colors. The complexity of the lines denotes the number of differences in spoligo-MIRU type profile between two nodes: solid lines (1, 2 or 3 differences), gray dashed lines (4 differences) and gray dotted lines (5 or more differences). Profiles with double alleles were not included in this analysis. MST was generated with Bionumerics (version 6.6, http://www.applied-maths.com/bionumerics).
