Table 1 Clinical characteristics at baseline.

From: Novel urinary glycan profiling by lectin array serves as the biomarkers for predicting renal prognosis in patients with IgA nephropathy

Clinical parameters

All patients (n = 142)

Renal outcome

P value

Good (G)

(n = 116)

Poor (P)

(n = 26)

Maleb

68 (48)

53 (46)

15 (58)

0.27

Age (years)a

42.7 ± 16.3

41.5 ± 15.0

48.2 ± 20.6

0.06

BMI (kg/m2)a

22.2 ± 3.2

22.3 ± 3.3

22.2 ± 3.0

0.88

SBP (mmHg)a

124.1 ± 17.7

122.1 ± 17.1

133.0 ± 18.2

 < 0.01

DBP (mmHg)a

77.9 ± 12.2

77.9 ± 12.3

77.9 ± 12.3

0.99

MAP (mmHg)a

93.3 ± 13.0

92.6 ± 13.1

96.2 ± 12.2

0.20

Hypertensionb

47 (33)

35 (30)

12 (46)

0.12

sCr (mg/dL)a

0.94 ± 0.37

0.92 ± 0.32

1.04 ± 0.55

0.14

eGFR (mL/min/1.73 m2)a

70.6 ± 25.9

70.3 ± 23.9

72.2 ± 34.1

0.74

IgA (mg/gL)a

310.7 ± 117.4

301.2 ± 108.4

352.9 ± 146.4

0.04

C3 (mg/dL)a

100.4 ± 18.0

99.7 ± 17.7

103.5 ± 19.5

0.33

IgA/C3a

3.2 ± 1.2

3.1 ± 1.1

3.5 ± 1.3

0.15

UP (g/day)a

0.73 (0.27–1.53)

0.69 (0.26–1.27)

0.90 (0.37–3.09)

0.04

Urine occult bloodc

124 (87)

101 (87)

23 (88)

0.57

Smoke (never/past/current)de

81 (62)/33 (25)/16 (12)

66 (63)/26 (25)/13 (12)

15 (60)/7 (28)/3 (12)

0.83

Re-biopsyc

25 (18)

19 (16)

6 (23)

0.40

ACE-I or ARBb

40 (28)

32 (28)

8 (31)

0.74

Calcium channel blockerb

30 (21)

22 (19)

8 (31)

0.18

Tonsillectomyb

86 (61)

74 (64)

12 (46)

0.09

Steroid therapyb

101 (71)

84 (72)

17 (65)

0.48

TSPb

83 (58)

71 (61)

12 (46)

0.16

  1. Data are mean ± standard deviation, n (%), or median (inter-quartile range) unless otherwise indicated.
  2. BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; sCr, serum creatinine; eGFR, estimated glomerular filtration rate; UP, urinary protein; ACE-I, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; TSP, tonsillectomy combined with steroid pulse therapy.
  3. aStudent’s t-test.
  4. bPearson’s chi-square test.
  5. cFisher’s exact test.
  6. dWilcoxon test.
  7. en = 130.