Figure 1
From: Ventral cochlear nucleus bushy cells encode hyperacusis in guinea pigs
Noise-overexposure results in temporary threshold shifts. (A) Following noise-overexposure (spectrum: green triangle), hearing thresholds for exposed animals were elevated immediately post-exposure (filled pink squares) compared to baseline (filled symbols with solid lines) and prior to surgery (open symbols with dashed lines). Hearing thresholds at baseline and prior to single-unit recordings were not significantly different between noise-exposed animals (purple squares) or non-exposed controls (black diamonds). (B) ABR W1 amplitude-intensity functions (AIFs) for noise-exposed (purple) and control (black) guinea pigs at baseline (filled symbols with solid lines) and pre-recording (open symbols with dashed lines). (C) Mean percent-change in startle amplitude from baseline to post-exposure for each GPIAS carrier band for noise-exposed (purple squares) and control (black diamonds) animals. Data shown are mean + /-SEM.
