Figure 1 | Scientific Reports

Figure 1

From: Detection of urinary miRNAs for diagnosis of clear cell renal cell carcinoma

Figure 1

The best urinary miRNA markers as derived by data bank analysis and algorithm. (A) Top 10 miRNAs overexpressed in ccRCC samples compared with their expression in kidney samples from healthy subjects (HSs), based on data bank analysis. (B) Algorithm used to calculate the probability for a miRNA to represent a urinary marker of ccRCC. Overexpression in ccRCC, expression in the kidney, bladder, and prostate (the latter used to calculate the score in men only *), and standard deviation (SD) of miRNA expression in normal tissue and ccRCC were calculated using the data bank values expressed as Log2. C, The top 10 miRNAs and their scores potentially representing the best urinary markers of ccRCC, as suggested by the algorithm.

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