Table 2 Not normalized miRNA levels in the urine samples of ccRCC patients as compared to urine samples of healthy subjects (HSs) (Log2 values). Urinary miRNA levels are compared to the overexpression of RNU6-2-normalized miRNAs in ccRCC specimens as compared to the corresponding adjacent non-cancerous kidney tissue samples.

From: Detection of urinary miRNAs for diagnosis of clear cell renal cell carcinoma

miRNA

INCREASED LEVELS (positive values, Log2) of miRNAs in the urine of ccRCC patients and OVEREXPRESSION of miRNAs (positive values, Log2) by ccRCC specimens

Urine

(mean of ccRCC samples vs mean of HS samples)

Tissue

(ccRCC samples vs correspondent adjacent non-cancerous

kidney tissue, see Table 1)

Folds

Passed KS test *

p value

(unpaired test)

Folds (p values)

miR-122

3.90

No

0.0032

5.74 (< 0.0001)

miR-1271

1.74

Yes

0.0150

0.32 (0.3250)

miR-15b

0.86

Yes

0.4890

1.38 (0.0017)

  1. *If Kolmogorov–Smirnov (KS) test (a normality test) was passed, the unpaired t-test was used to calculate p value, otherwise the Mann–Whitney test was used.
Back to article page