Table 2 Biodistribution of ¹⁸F-mFBG 4 h after injection of mice bearing SK-N-BE(2)C xenografts, pre-treated with AZD2014 (20 mg/kg/day) or vehicle control (DMSO 10%, PEG400 90%) for 1, 3 or 7 days.

3

3

3

3

3

3

0.18 ± 0.02

0.18 ± 0.04

0.18 ± 0.08

0.16 ± 0.02

0.17 ± 0.06

0.32 ± 0.14

4.38 ± 1.68

4.34 ± 2.38

3.64 ± 0.89

3.20 ± 0.43^a

5.87 ± 2.80

4.17 ± 1.63

1.22 ± 0.37

1.27 ± 0.68

1.15 ± 0.23

1.04 ± 0.12

1.86 ± 0.64

1.33 ± 0.36

0.79 ± 0.36

0.98 ± 0.04

1.13 ± 0.47

0.89 ± 0.13

1.09 ± 0.16

1.02 ± 0.15

3.19 ± 0.63

2.93 ± 0.82

2.08 ± 1.29

2.27 ± 1.06

1.75 ± 0.67

1.64 ± 0.46

1.94 ± 0.30

1.63 ± 0.69

1.96 ± 0.02

1.74 ± 0.23

2.15 ± 0.30

2.64 ± 0.46

1.01 ± 0.18

1.09 ± 0.42

1.25 ± 0.51

1.29 ± 0.51

2.81 ± 1.72

3.08 ± 1.80

2.76 ± 1.14

3.29 ± 1.01

2.39 ± 0.10

3.95 ± 1.53

2.17 ± 1.01

2.61 ± 1.19

4.50 ± 0.24^b

4.79 ± 1.21

5.32 ± 0.11

4.88 ± 1.28

6.22 ± 0.35

6.87 ± 1.86

0.60 ± 0.13

0.59 ± 0.16

0.53 ± 0.19

0.55 ± 0.09

0.67 ± 0.07

0.75 ± 0.02

5.14 ± 0.38^b

5.47 ± 0.45^b

5.15 ± 0.78^b

5.32 ± 1.51^b 

6.08 ± 2.45

8.08 ± 0.72

4.98 ± 2.18^c

4.55 ± 2.15^c

1.64 ± 0.45

2.42 ± 2.57

1.13 ± 0.20

0.63 ± 0.54

15.27 ± 5.32

17.72 ± 2.35

14.47 ± 4.61

23.76 ± 6.20

15.55 ± 13.55

8.06 ± 2.57

4.44 ± 0.94

5.74 ± 1.77

4.89 ± 1.48

7.06 ± 1.79

3.36 ± 1.90

3.50 ± 1.62