Figure 3 | Scientific Reports

Figure 3

From: Quantitative and functional characteristics of circulating and bone marrow PD-1- and TIM-3-positive T cells in treated multiple myeloma patients

Figure 3

Frequency of PD-1+ and TIM-3+ T cell subsets in bone marrow samples of healthy donors and multiple myeloma patients. Graphs show relative counts bone marrow CD4+PD-1+ (A), CD4+TIM-3+ (B), CD8+PD-1+ (D), CD8+TIM-3+ (E) T cells and double positive CD4+PD-1+TIM-3+ (C) and CD8+PD-1+TIM-3+ (F) T cell subsets in MM patients in complete remission or partial response (CR/PR, n = 30, light grey boxes) and MM patients with progressive disease (n = 10, dark grey boxes). Data are expressed as median, interquartile range and range of minimum and maximum values. P values are assessed with Mann–Whitney U-test (*PU < 0.05). Generated using GraphPad Prism 5.0 (GraphPad Software, Inc., San Diego, CA, USA; https://www.graphpad.com/).

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