Table 4 Correlation analysis between circulating and bone marrow PD-1+ and TIM-3+ T cell subsets in multiple myeloma patients.

From: Quantitative and functional characteristics of circulating and bone marrow PD-1- and TIM-3-positive T cells in treated multiple myeloma patients

Cell subset in PB and BM

% of CD4+ or CD8+ T cells

% of lymphocytes

CD4+PD-1+

rS = 0.43, P = 0.027, n = 26

rS = 0.50, P = 0.0090, n = 26

CD4+TIM-3+

rS = 0.020, P = 0.92, n = 26

rS = 0.38, P = 0.056, n = 26

CD8+PD-1+

rS = 0.51, P = 0.0078, n = 26

rS = 0.52, P = 0.0066, n = 26

CD8+TIM-3+

rS = 0.52, P = 0.0062, n = 26

rS = 0.61, P = 0.00091, n = 26

CD4+PD-1+TIM-3+

rS = 0.25, P = 0.24, n = 26

rS = 0.34, P = 0.10, n = 26

CD8+PD-1+TIM-3+

rS = 0.46, P = 0.025, n = 26

rS = 0.46, P = 0.026, n = 26

  1. Spearman’s rank correlation was used to evaluate associations for the studied variables.