Figure 1 | Scientific Reports

Figure 1

From: Epithelial loss of mitochondrial oxidative phosphorylation leads to disturbed enamel and impaired dentin matrix formation in postnatal developed mouse incisor

Figure 1

Histochemical localization of COX/SHD-staining in cells of the developing incisor of control and mutant K320E-TwinkleEpi mice at P3. In P3 control mice COX/SHD is detected in stem cells of the cervical loop, in cells of the enamel epithelium and in odontoblasts (A–D). In P3 K320E-TwinkleEpi mice COX/SHD staining is localized in cells of the dental papilla and in odontoblasts (E–H). However, no brown COX staining is found in the cervical loop or in the layers of the enamel epithelium (E–H). a, ameloblasts; dp, dental papilla; iee, inner enamel epithelium; la-cl, labial cervical loop; o, odontoblasts; oee, outer enamel epithelium; pl, papillary layer; si, stratum intermedium; sr, stellate reticulum; Scale bars: A,C,E,G = 200 µm; B,D,F,H = 50 µm.

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