Figure 6
Crystal structure analysis of PorA. (A) Amino acid sequence of PorA. The core fragment used for crystallization is shown in black and the region removed by protease is in gray. The signal peptide region is colored in yellow. β-strands are indicated by blue bars with labels. The residues not included in the structure model are shown in italics. (B) Structure of the core fragment of PorA. The model is color coded from blue to red from the N- to the C-terminus. (C) Structure of the mannose-binding lectin domain of FimH in complex with propynyl biphenyl α-d-mannoside (PDB ID: 4av5). The model is color coded from blue to red from the N- to the C-terminus. The ligand molecule is drawn in stick model with oxygen atoms colored red and carbon atoms colored gray.
