Table 2 Clinical outcomes.

From: Comparison of pre- and postoperative myocardial injuries on mortality after non-cardiac surgery: a retrospective analysis using an inverse probability weighting adjustment

 

n (%)

Univariate analysis

IPW analysis

Unadjusted HR (95% CI)

p value

Adjusted HR (95% CI)

p value

30-day mortality

Normal

44 (1.4)

1

 

1

 

Preoperative myocardial injury

74 (10.7)

8.31 (5.72–12.07)

 < 0.001

3.12 (1.62–6.01)

0.001

Postoperative myocardial injury

56 (7.4)

2.36 (1.94–2.88)

 < 0.001

4.49 (2.34–8.60)

 < 0.001

Pre- vs. postoperative myocardial injury

 

0.67 (0.47–0.95)

0.02

1.44 (0.79–2.64)

0.45

In-hospital death

 

Normal

65 (2.0)

1

 

1

 

Preoperative myocardial injury

97 (14)

3.33 (2.42–4.60)

 < 0.001

2.87 (0.95–3.68)

0.01

Postoperative myocardial injury

71 (9.4)

1.62 (1.37–1.92)

 < 0.001

2.32 (1.16–4.65)

0.001

Pre- vs. postoperative myocardial injury

 

0.80 (0.59–1.09)

0.16

1.24 (0.68–2.26)

0.34

Overall cardiovascular death

Normal

201 (6.3)

1

 

1

 

Preoperative myocardial injury

71 (10.2)

2.07 (1.58–2.72)

 < 0.001

1.30 (0.89–1.89)

0.18

Postoperative myocardial injury

71 (9.4)

1.29 (1.13–1.48)

 < 0.001

1.61 (1.16–2.23)

0.004

Pre- vs. postoperative myocardial injury

 

0.81 (0.58–1.13)

0.21

1.21 (0.70–2.10)

 > 0.99

Overall all-cause death

Normal

596 (18.7)

1

 

1

 

Preoperative myocardial injury

233 (33.6)

2.24 (1.92–2.60)

 < 0.001

1.37 (1.08–1.74)

0.009

Postoperative myocardial injury

218 (28.8)

1.30 (1.20–1.41)

 < 0.001

1.51 (1.24–1.85)

 < 0.001

Pre- vs. postoperative myocardial injury

 

0.77 (0.64–0.93)

0.006

1.10 (0.79–1.54)

 > 0.99

 

n (%)

Univariate analysis

IPW analysis

Unadjusted OR (95% CI)

p value

Adjusted OR (95% CI)

p value

Type 1 myocardial infarction

Normal

10 (0.3)

1

 

1

 

Preoperative myocardial injury

8 (1.2)

3.70 (1.41–9.41)

0.006

2.07 (0.59–7.25)

0.49

Postoperative myocardial injury

16 (2.1)

2.62 (1.77–3.96)

 < 0.001

7.12 (2.54–19.99)

 < 0.001

Pre- vs. postoperative myocardial injury

 

1.85 (0.81–4.60)

0.16

3.44 (1.02–11.56)

0.04

Coronary revascularization

Normal

6 (0.2)

1

 

1

 

Preoperative myocardial injury

3 (0.4)

2.30 (0.48–8.73)

0.24

2.08 (0.33–12.99)

0.99

Postoperative myocardial injury

8 (1.1)

2.38 (1.40–4.15)

0.001

6.29 (1.58–24.98)

0.004

Pre- vs. postoperative myocardial injury

 

2.46 (0.71–11.28)

0.18

3.03 (0.49–18.83)

0.44

Atrial fibrillation

Normal

67 (2.1)

1

 

1

 

Preoperative myocardial injury

52 (7.5)

3.77 (2.59–5.45)

 < 0.001

3.34(1.76–6.35)

 < 0.001

Postoperative myocardial injury

47 (6.2)

1.76 (1.45–2.12)

 < 0.001

2.61 (1.54–4.43)

 < 0.001

Pre- vs. postoperative myocardial injury

 

0.82 (0.54–1.23)

0.34

0.78 (0.39–1.57)

0.99

Heart failure

Normal

3 (0.1)

1

 

1

 

Preoperative myocardial injury

8 (1.2)

12.36 (3.56–56.52)

 < 0.001

15.22 (2.49–93.16)

 < 0.001

Postoperative myocardial injury

4 (0.5)

2.37 (1.11–5.35)

0.02

4.15 (0.62–28.02)

0.22

Pre- vs. postoperative myocardial injury

 

0.46 (0.12–1.45)

0.2

0.27 (0.05–1.58)

0.99

AKI, any

Normal

205 (6.4)

1

 

1

 

Preoperative myocardial injury

172 (24.8)

4.79 (3.83–5.98)

 < 0.001

2.13 (1.43–3.19)

 < 0.001

Postoperative myocardial injury

219 (29.0)

2.43 (2.19–2.71)

 < 0.001

3.11 (2.30–4.21)

 < 0.001

Pre- vs. postoperative myocardial injury

 

1.24 (0.98–1.56)

0.07

1.46 (0.96–2.22)

0.1

  1. AKI acute kidney injury.
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