Table 2 Pre-donation characteristics and differences between clusters.

From: Psychosocial risk factors for impaired health-related quality of life in living kidney donors: results from the ELIPSY prospective study

 

All partici-pants (n = 60)

Cluster 1 (n = 43)

Cluster 2 (n = 17)

t/x2

p

Univariate logistic regression p§

Mean (sd)/n (%)

Mean (sd)/n (%)

Mean (sd)/n (%)

Socio-demographic characteristics

Age (years)

50.18 (11.73)

51.41 (11.40)

47.05 (12.31)

1.306

0.197

0.191

Gender (female)

36 (60.0%)

25 (58.1%)

11 (64.7%)

0.219

0.640

0.638

Donor-recipient relationship (genetically related)

32 (53.3%)

24 (55.8%)

8 (47.1%)

0.375

0.540

0.541

Marital status

Without partner (single, divorced, widowed)

22 (36.7%)

14 (32.6%)

8 (47.1%)

1.140

0.565

0.298

With partner

38 (63.3%)

29 (67.4%)

9 (52.9%)

   

Level of studies

No academic, elementary

19 (32.2%)

13 (31.0%)

6 (35.3%)

0.104

0.747

0.748

Intermediate

22 (37.3%)

15 (35.7%)

7 (41.2%)

0.154

0.694

0.695

Upper studies

18 (30.5%)

14 (33.3%)

4 (23.5%)

0.549

0.545

0.452

Psychometric instruments

Quality of life

Anamnestic comparative self-assessment, range − 5 (worst period) to 5 (best period)

2.79 (1.74)

2.59 (1.85)

3.29 (1.33)

 − 1.335

0.188

0.158

Item short form survey (SF-36), range 0–100

Physical functioning (PF)

53.87 (5.45)

55.09 (3.35)

50.78 (8.12)

2.119

0.048

 

Role physical (RP)

55.09 (3.01)

55.02 (3.29)

55.26 (2.21)

 − 0.283

0.778

 

Bodily pain (BP)

58.43 (5.28)

58.69 (4.59)

57.78 (6.85)

0.504

0.619

 

General health (GH)

56.28 (7.01)

57.05 (6.34)

54.32 (8.36)

1.216

0.236

 

Vitality (VT)

58.00 (7.47)

57.40 (7.81)

59.54 (6.51)

 − 0.999

0.322

 

Social functioning (SF)

54.90 (4.83)

54.72(5.45)

55.36 (2.77)

 − 0.459

0.648

 

Role emotional (RE)

54.60 (3.64)

54.37 (4.24)

55.17 (1.04)

 − 0.762

0.449

 

Mental health (MH)

55.48 (6.58)

54.40 (6.94)

58.21 (4.71)

 − 2.078

0.042

 

Mental health status

Hospital anxiety and depression scale

Anxiety scale, range 0–21

3.70 (2.84)

3.91 (2.88)

3.18 (2.74)

0.892

0.376

0.358

Depression scale, range 0–21

1.75 (1.94)

1.93 (2.04)

1.29 (1.65)

1.146

0.257

0.231

Coping strategies

Optimism, life orientation test-revised (sum of items) range 6–30

23.90 (4.44)

24.14 (4.58)

23.29 (4.17)

0.661

0.511

0.508

Sense of coherence, range 1–7

5.55 (0.94)

5.56 (0.90)

5.52 (1.07)

0.146

0.885

0.882

Personality

Eysenck personality questionnaire-revised-abbreviated

Neuroticism scale, range 0–6

0.98 (1.20)

1.00 (1.25)

0.94 (1.06)

0.177

0.860

0.857

Extraversion scale, range 0–6

4.10 (1.76)

4.14 (1.78)

4.00 (1.79)

0.273

0.786

0.782

Psychoticism scale, range 0–6

1.41 (1.07)

1.33 (1.11)

1.63 (0.96)

 − 0.956

0.343

0.334

Socioeconomic status

English longitudinal study of ageing range 1 (worst off) to 10 (best off)

Socioeconomic status range 1 (worst off) to 10 (best off)

6.31 (1.43)

6.35 (1.42)

6.20 (1.47)

0.345

0.732

0.726

Ad hoc items

Psychiatric history

Have you ever seen a counselor, psychiatrist or psychologist? (yes)

11 (18.6%)

10 (23.3%)

1 (6.3%)

2.223

0.259

0.104

Motivations/reasons for donation

Personal responsibility and obligation (mean of items) range 1 (not relevant) to 5 (very important)

2.07 (0.89)

1.92 (0.77)

2.47 (1.07)

 − 2.081

0.043

0.046

Donors’ desire to stop their recipients’ suffering and/or save their lives (mean of items) range 1 (not relevant) to 5 (very important)

3.40 (0.90)

3.27 (0.87)

3.87 (0.83)

 − 2.313

0.025

0.022

Donors’ fears and concerns about donation’s own consequences and family and friends opinion (mean of items) range 1 (not relevant) to 5 (very important)

1.33 (0.55)

1.27 (0.46)

1.47 (0.71)

 − 1.229

0.224

0.236

Challenges involving the donation decision; including personal growth and financial implications (mean of items) Range 1 (not relevant) to 5 (very important)

2.42 (0.99)

2.33 (1.03)

2.64 (0.86)

 − 1.040

0.303

0.297

Decision making

Necessity of some time to think over donation

Strongly disagree/Disagree

35 (60.3%)

26 (63.4%)

9 (52.9%)

0.551

0.458

0.460

Agree/strongly agree

23 (39.7%)

15 (36.6%)

8 (47.1%)

   

Risk assessment

Necessity of more information regarding the surgery and its risks (yes)

6 (10.2%)

2 (4.8%)

4 (23.5%)

4.667

0.097

0.041

Recipients’ characteristics

Recipients’ socio-demographic characteristics

Weight (Kg)

77.64 (19.07)

79.37 (20.33)

73.09 (14.89)

1.122

0.267

0.256

Recipient baseline

African ancestry (yes)

2 (3.4%)

1 (2.4%)

1 (5.9%)

0.453

0.497

0.521

Indication of transplantation

Urological

4 (6.9%)

4 (9.5%)

0 (0%)

1.637

0.567

 

Glomerulopathy

17 (29.3%)

14 (33.4%)

3 (18.8%)

1.189

0.347

 

Nephroangioesclerosis

7 (12.1%)

4 (9.5%)

3 (18.7%)

0.929

0.381

 

Diabetes Mellitus

2 (3.4%)

0 (0%)

2 (12.5%)

5.438

0.073

 

Others

8 (13.8%)

6 (14.3%)

2 (12.5%)

0.031

1.000

 

Unknown

12 (20.7%)

10 (23.8%)

2 (12.5%)

0.903

0.479

 

Polycystic kidney disease

8 (13.8%)

4 (9.5%)

4 (25.0%)

2.334

0.198

 

Registration in waiting list for deceased donor (yes)

35 (60.4%)

22 (53.7%)

13 (76.5%)

2.613

0.144

0.098

Dialysis before transplantation (yes)

39 (67.2%)

27 (65.9%)

12 (70.6%)

0.122

0.727

0.725

Previous kidney transplantation (yes)

6 (10.3%)

5 (12.2%)

1 (5.9%)

0.516

0.660

0.451

Previous other organ transplantation (yes)

0 (0%)

0 (0%)

0 (0%)

   

High immunological risk (yes)

11 (19.6%)

7 (17.1%)

4 (26.7%)

0.640

0.461

0.434

High risk of recurrence (yes)

4 (7.0%)

3 (7.3%)

1 (6.3%)

0.020

1.000

0.886

Presence of serious co-morbid diseases (yes)

11 (19.3%)

8 (19.5%)

3 (18.8%)

0.004

1.000

0.948

  1. Fisher’s exact test.
  2. Not assuming equality of variances.
  3. §Any p-value remained statistically significant after FDR correction.
  4. SF-36 T scores (> 55 is higher than average, < 45 is lower than average).