Figure 7
From: Positioning of an unprecedented spiro[5.5]undeca ring system into kinase inhibitor space
The control of LPS-induced inflammation by compounds 2a and 2d in BV-2 cells: (A) the secreted level of PGE2 as a pro-inflammatory mediator, (B) TNF-α, (C) IL-6, and (D) IL-1β as pro-inflammatory cytokines.
