Table 2 Top 5 canonical pathways involved in late-onset fetal growth restriction.

From: Maternal proteomic profiling reveals alterations in lipid metabolism in late-onset fetal growth restriction

Canonical pathways

p value

Molecules

LXR/RXR Activation

2.17E−07

APOE, APOC2, PLTP, FGA, APOC3

FXR/RXR Activation

2.56E−07

APOE, APOC2, PLTP, FGA, APOC3

LPS/IL-1 Mediated Inhibition of RXR Function

8.29E−05

APOE, APOC2, PLTP, FABP5

Atherosclerosis Signaling

3.66E−04

APOE, APOC2, APOC3

IL-12 Signaling and Production in Macrophages

5.67E−04

APOE, APOC2, APOC3

  1. APOC2 Apolipoprotein C2, APOC3 Apolipoprotein C3, APOE Apolipoprotein E, FABP5 Fatty acid-binding protein 5, FGA Fibrinogen alpha chain, FXR Farsenoid X receptor, IL-1 Interleukin-1, IL-12 Interleukin-12, LPS Lipopolysaccharide, LXR Liver X receptor, PLTP Phospholipid transfer protein, RXR Retinoid X receptor.
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