Table 3 Top 25 biological processes involved in late-onset fetal growth restriction.

From: Maternal proteomic profiling reveals alterations in lipid metabolism in late-onset fetal growth restriction

Diseases or Functions Annotation

p value

Molecules

Efflux of cholesterol

4.80E−09

ADIPOQ, APOC2, APOC3, APOE, PLTP

Efflux of phospholipid

4.89E−09

APOC2, APOC3, APOE, PLTP

Adhesion of blood cells

1.96E−07

ADIPOQ, APOE, FGA, GP1BA, LTF, PLTP

Fatty acid metabolism

2.02E−07

ADIPOQ, APOC2, APOC3, APOE, EGFR, LTF, PLTP

Dyslipidemia

1.55E−06

ADIPOQ, APOC2, APOC3, APOE

Adhesion of immune cells

2.49E−06

ADIPOQ, APOE, FGA, LTF, PLTP

Synthesis of fatty acid

2.62E−06

APOC2, APOC3, APOE, EGFR, LTF

Binding of cells

2.77E−06

ADIPOQ, APOE, EGFR, GP1BA, LGALS3BP, LTF

Cell movement of hepatoma cell lines

4.84E−06

ADIPOQ, EGFR, LYVE1, TAGLN2

Concentration of lipid

6.24E−06

ADIPOQ, APOC3, APOE, EGFR, PLTP

Binding of blood cells

1.40E−05

ADIPOQ, APOE, GP1BA, LTF

Adhesion of lymphoma cell lines

1.66E−05

APOE, EGFR, FGA

Homeostasis of lipid

1,90E−05

APOC2, APOC3, APOE

Adhesion of tumor cell lines

3.28E−05

APOE, EGFR, FGA, GP1BA, LTF

Progression of digestive organ tumor

3.47E−05

APOE, EGFR

Progression of carcinoma

4.46E−05

APOE, EGFR

Binding of myeloid cells

4.68E−05

ADIPOQ, APOE, LTF

Aggregation of cells

4.83E−05

EGFR, FGA, GP1BA, PSG2

Hyperlipidemia

5.39E−05

APOC2, APOC3, APOE

Binding of macrophages

6.80E−05

ADIPOQ, APOE

Fibrinolysis

8.16E−05

FGA, GP1BA

Lower respiratory tract disorder

9.59E−05

EGFR, FABP5, LTF, PLTP

Fibrin clot

9.64E−05

FGA, GP1BA

Homeostasis of triacylglycerol

9.64E−05

APOC2, APOC3

Binding of fibroblasts

1.12E−04

APOE, LGALS3BP

  1. ADIPOQ Adiponectin, APOC2 Apolipoprotein C-II, APOC3 Apolipoprotein C-III, APOE Apolipoprotein E, EGFR Epidermal growth factor receptor, FABP5 Fatty acid-binding protein 5, FGA Fibrinogen alpha chain, GP1BA Platelet glyprotein Ib alpha chain, LGALS3BP Galectin-3-binding protein, LTF Lactotransferrin precursor, LYVE1 Lymphatic vessel endothelial hyaluronan receptor 1, PLTP Phospholipid transfer protein, PSG2 Pregnancy specific beta-1-glycoprotein 2.