Table 1 Baseline patient characteristics.

From: Targeting continuity of care and polypharmacy to reduce drug–drug interaction

Variables

Low COC group

High COC group

P valuea

All patients

N

1,159,069

1,159,697

 

2,318,766

COCI [mean(SD)]

0.15(0.06)

0.46(0.21)

 < 0.001

0.30(0.22)

Age in 2011 [mean(SD)]

74.71(6.94)

74.72(6.96)

0.382

74.71(6.95)

Age group [n (%)]

  

< 0.001

 

65–74

629,334(54.30)

634,364(54.70)

 

1,263,698(54.50)

75–84

412,402(35.58)

406,122(35.02)

 

818,524(35.30)

85+

117,333(10.12)

119,211(10.28)

 

236,544(10.20)

Gender [n (%)]

  

< 0.001

 

Male

532,303(49.26)

548,359(50.74)

 

1,080,662(46.61)

Female

626,766(50.62)

611,338(49.38)

 

1,238,104(53.39)

Physician visits [mean(SD)]

35.05(23.44)

25.25(17.91)

< 0.001

30.15(21.42)

Physician visits frequency [n(%)]

  

< 0.001

 

Low

306,827(26.47)

487,507(42.04)

 

794,334(34.26)

Intermediate

347,785(30.01)

422,063(36.39)

 

769,848(33.20)

High

504,457(43.52)

250,127(21.57)

 

754,584(32.54)

No. of prescribed medications [mean(SD)]

11.29(6.41)

8.17(4.81)

 < 0.001

9.73(5.88)

Polypharmacy status [n(%)]

  

< 0.001

 

No

66,193(5.71)

141,473(12.20)

 

207,666(8.96)

Yes

1,092,876(94.29)

1,018,224(87.80)

 

2,111,100(91.04)

Drug–drug interaction events [n(%)]

  

 < 0.001

 

No

1,104,885(95.32)

1,135,212(97.88)

 

2,240,097(96.60)

Yes

54,184(4.67)

24,485(2.11)

 

78,669(3.39)

  1. COCI continuity of care index, SD standard deviation.
  2. aChi-square tests were used for comparisons between age group, gender, physician visits frequency, polypharmacy status, and DDI events, and t tests were used to compare COCI, physician visits, and number of prescribed medications.