Table 2 Comparative data (mean ± SD) analysis of number of smoked cigarettes per day, exhaled CO, STT, peripheral oxygenation, and lung function values between the groups at Baseline and after 6 months. a, p < 0.001 versus baseline; b, p < 0.001 versus smokers at the same time; c, p = 0.002 versus baseline; d, p = 0.020 versus baseline; e, p = 0.040 versus smokers at the same time.

From: Smoking load reduction is insufficient to downregulate miR-301b, a lung cancer promoter

 

Quitters

n = 18

Smokers

n = 10

Baseline

6-month

Baseline

6-month

Cigarettes per day (n)

22 ± 7

0 ± 0a,b

23 ± 10

10 ± 10c

Exhaled CO (ppm)

10 ± 9

3 ± 2a,b

13 ± 6

8 ± 3d

STT (min)

16.0 ± 12.0

8.5 ± 8.0d,e

23.0 ± 19.0

16.0 ± 16.1

Peripheral oxygenation (%)

95 ± 2

96 ± 1

94 ± 2

94 ± 2

FVC (L)

3.41 ± 0.87

3.37 ± 0.86

3.32 ± 1.10

3.20 ± 1.00

FVC pred (%)

89.2 ± 12.2

86.4 ± 14.1

90.3 ± 18.3

87.6 ± 19.0

FEV1 (L)

2.45 ± 0.67

2.38 ± 0.64

2.38 ± 0.78

2.52 ± 0.90

FEV1 pred (%)

81.0 ± 14.2

78.0 ± 15.0

80.0 ± 18.0

85.6 ± 21.0

FEV1/FVC ratio

0.72 ± 0.07

0.71 ± 0.07b

0.71 ± 0.11

0.78 ± 0.06

  1. STT, saccharine transit time test; FVC, forced vital capacity; pred, predicted; FEV1, forced expiratory volume in one second.
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