Figure 4 | Scientific Reports

Figure 4

From: Analysis of enteric nervous system and intestinal epithelial barrier to predict complications in Hirschsprung’s disease

Figure 4

Paracellular and transcellular permeabilities in the 3 HSCR subgroups (white bars) (HSCR patients with Hirschsprung-associated enterocolitis (HAEC), with obstructive symptoms or diarrhoea (OS/D) and without complications (w/oC)) and in ARM (grey bar) patients. (A) Paracellular permeability measured with sulfonic acid (SA) flux (*p = 0.02; **p = 0.0095; ***p = 0.016), and (B) transcellular permeability measured with and Horse Radish Peroxydase (HRP) flux (*p = 0.013; **p = 0.017; ***p = 0.029). Mucosal expression of (C) caveolin-1 (*p = 0.03; **p = 0.04) and (D) clathrin in Western Blot. Medians with ranges. AU: arbitrary unit.

Back to article page