Figure 5

Expression of (A) TNFα expression (*p = 0.02), (B) TLR2 expression (*p = 0.01), and (C) TLR4 expression (*p = 0.02) in qPCR in the 3 HSCR subgroups (white bars) (HSCR patients with Hirschsprung-associated enterocolitis (HAEC), with obstructive symptoms or diarrhoea (OS/D) and without complications (w/oC)) and in ARM (grey bar) patients. Medians with ranges. (D) Correlation between TNFα and TLR2 expressions (r = 0.73; 95% IC 0.48–0.87; p < 0.0001), (E) between TNFα and TLR4 expressions (r = 0.78; 95% IC 0.56–0.89; p < 0.0001), and (F) between TLR4 and TLR2 expressions (r = 0.82; 95% IC 0.63–0.92; p < 0.0001).