Table 1 Clinical characteristics of the study cohort.

From: Atherogenic index of plasma and coronary artery calcification progression beyond traditional risk factors according to baseline coronary artery calcium score

 

Total (n = 12,326)

Quartiles of AIP

P

I (lowest) (n = 3103) 0.620 − 0.170

II (n = 3064) 0.171 − 0.369

III (n = 3085) 0.370 − 0.575

IV (highest) (n = 3074) 0.576 − 1.738

Age, years

51.7 ± 8.5

51.6 ± 9.0

52.1 ± 8.6

52.2 ± 8.4

50.9 ± 7.9

 < 0.001

Male, n (%)

10,382 (84.2)

2,134 (68.8)

2,573 (84.0)

2,793 (90.5)

2,882 (93.8)

 < 0.001

Systolic BP, mmHg

119.6 ± 15.0

117.5 ± 15.1

119.5 ± 15.1

120.1 ± 15.0

121.1 ± 14.6

 < 0.001

Diastolic BP, mmHg

75.0 ± 10.5

72.9 ± 10.7

75.0 ± 10.5

75.5 ± 10.4

76.8 ± 10.2

 < 0.001

BMI, kg/m2

24.6 ± 2.8

23.3 ± 2.7

24.3 ± 2.6

25.0 ± 2.6

25.7 ± 2.6

 < 0.001

Traditional risk factors

Hypertension, n (%)

4,016 (33.6)

806 (27.0)

965 (32.6)

1,095 (36.6)

1,150 (38.3)

 < 0.001

Diabetes, n (%)

1,703 (13.8)

300 (9.7)

367 (12.0)

502 (16.3)

534 (17.4)

 < 0.001

Hyperlipidemia, n (%)

3,455 (28.0)

587 (18.9)

767 (25.0)

926 (30.0)

1,175 (38.2)

 < 0.001

Obesity, n (%)

5,178 (42.2)

760 (24.6)

1,153 (37.8)

1,468 (47.8)

1,797 (58.6)

 < 0.001

Current smoking, n (%)

3,229 (28.5)

529 (18.6)

669 (23.9)

891 (31.4)

1,140 (40.1)

 < 0.001

Laboratory

Total cholesterol, mg/dL

197.5 ± 34.0

191.9 ± 32.1

195.5 ± 33.6

198.0 ± 34.0

204.6 ± 35.1

 < 0.001

Triglyceride, mg/dL

141.7 ± 89.4

69.9 ± 19.9

103.2 ± 21.9

143.1 ± 29.7

250.9 ± 108.1

 < 0.001

HDL-C, mg/dL

53.3 ± 16.0

68.3 ± 19.3

54.7 ± 10.9

48.5 ± 9.0

41.8 ± 7.7

 < 0.001

LDL-C, mg/dL

122.0 ± 31.7

110.2 ± 30.8

123.8 ± 31.0

128.0 ± 30.5

126.1 ± 31.5

 < 0.001

Fasting glucose, mg/dL

97.8 ± 20.3

92.9 ± 16.3

96.6 ± 17.8

99.4 ± 20.7

102.3 ± 24.4

 < 0.001

HbA1C, %

5.7 ± 0.7

5.5 ± 0.6

5.6 ± 0.7

5.7 ± 0.8

5.8 ± 0.9

 < 0.001

AIP

0.377 ± 0.295

0.007 ± 0.129

0.274 ± 0.057

0.469 ± 0.058

0.759 ± 0.154

 < 0.001

  1. Values are presented as the mean ± standard deviation or number (%).
  2. AIP atherogenic index of plasma, BMI body mass index, BP blood pressure, HbA1C glycated hemoglobin A1C, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol.