Figure 4

Intraperitoneal administration of PZ-DHA results in absorption into the systemic circulation of Balb/c female mice. PZ-DHA (100 mg/kg) was administered by intraperitoneal injection to Balb/c female mice. Blood collection was performed and serum was separated. PZ-DHA was identified and quantified using a calibration curve (R2 = 0.99) generated using a standard series of PZ-DHA concentrations made in mouse serum. PZ-DHA concentration was plotted against time. The elimination rate of PZ-DHA was determined using a semi-log curve of PZ-DHA concentration vs. time curve.