Figure 1

CYP1A2 and CYP3A4 expression in patients’ peripheral leukocytes (N = 96). (A) CYP1A2 mRNA levels in the patients carrying only wild-type CYP1A2 allele (CYP1A2*1/*1) and in those carrying one or two CYP1A2*1F alleles. (B) CYP3A4 mRNA levels in the patients with CYP3A4*1/*1, CYP3A4*1/*1B and CYP3A4*1/*22 genotypes. **P = 0.001.