Figure 4
From: Mesoscopic cortical network reorganization during recovery of optic nerve injury in GCaMP6s mice
Functional connectivity matrix. (A) Left panel: Schematic of connectivity information provided by the correlation matrix. L- and R- indicates left and right hemispheres respectively. Yellow and green zones: correlation values between regions of the same hemisphere (left and right respectively). Purple zone: correlation values between regions of both hemispheres. Dotted white line: correlation between homotopic regions from the two hemispheres. Right panel: Correlation matrix (averaged from n = 9 mice and Fisher Z-transformed) at d-2 with 3 representative connections used in panel C (black boxes). (B) First line: Seed Pixel Correlation matrix averaged from n = 9 mice for 4 selected days (for sake of clarity) before and after ONC. White diamonds indicate the statistical difference (p < 0.05). Second line: Differential correlation matrix (difference in correlation between each day and the baseline). (C) Evolution of the correlation for 30 days (9 measures) in three representative connections (right areas AM and PM, right areas V1 and bilateral areas PM, as shown in panel (A) having the deepest change and significance. (*) Indicates Wilcoxon test, between baseline and current day and which provided p values under 0.05.
