Figure 5 | Scientific Reports

Figure 5

From: Cell–cell fusion of mesenchymal cells with distinct differentiations triggers genomic and transcriptomic remodelling toward tumour aggressiveness

Figure 5

Hybrids presenttranscriptomic remodelling. (a) Schema of pathways overexpressed in parental cells compared to hybrids and in hybrids compared to parental cells. Each arrow indicates enriched Gene Ontologies in different cellular entities. On the top, pathways enriched in hybrids compared to RST DsRed are indicated in orange square. No pathway is enriched in RST DsRed compared to hybrids as indicated in the red square. On the bottom, pathways enriched in hybrids compared to myoblast cells are showed in orange square. Muscular differentiation pathway enriched in myoblasts compared to hybrids is indicated in green square. (b) Transcriptomic profile clustering of parental and hybrid cell lines.

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