Figure 4
From: Age related extracellular matrix and interstitial cell phenotype in pulmonary valves

Proteomic profiles of PV leaflets from young and adult pigs. (A) The Venn diagram illustrates the overlap and unique proteins identified in young and adult groups; (B) volcano plot showing –log (p-value) versus protein fold change (Log2) of all identified proteins. (Red, 60 up-regulated proteins; green, 27 down-regulated proteins; grey, not significantly changed for Adult vs. Young). The solid lines represent a twofold difference in abundance and a p-value < 0.05. (C) Heatmap of the 50 most upregulated and downregulated proteins.