Figure 5

Double immunofluorescence assays for CD34 and CD31 in prostate histological sections of adult (3 months old) and senile (24 months old) male Mongolian gerbils. (A–D) The CD34 immunolabeling in adult animals (3 months of age) is found dispersed in the prostate stroma in blood vessels, in which it colocalizes with CD31. It is possible to verify a telocyte in the prostate stroma, which is CD34-positive and CD31-negative, it has a long CD34-positive telopode. (E–H) Another telocyte is observed, with a telopode reaching a prostatic alveolus. (I–L) In the prostate of senile animals (24 months of age), it is possible to observe the CD34 immunostaining typical of a telocyte in the perialveolar region. (M–P) Immunolabeling for telocytes is also observed close to the prostate alveoli in the interstitium. PA (Prostate alveoli), U (Urethra), Inserts (Detail of telocytes, with emphasis on telopodes), BV (Blood vessel), Arrow (podomers), Arrowhead (podoms), Bar (50 µm).