Table 2 Comparison of mitochondrial respiration parameters and mitochondrial oxidative stress parameters between normal and MCI participants.

From: Cognitive impairment is associated with mitochondrial dysfunction in peripheral blood mononuclear cells of elderly population

Variables

Normal (nā€‰=ā€‰428)

MCI (nā€‰=ā€‰469)

p-value

Mitochondrial respiration parameters

Non-Mitochondrial respiration (OCR, pmol/min)

24.00 (10.33)

23.86 (10.11)

0.857

Mitochondrial Basal respiration (OCR, pmol/min)

57.73 (33.17)

56.00 (33.34)

0.476

Mitochondrial proton leak (OCR, pmol/min)

12.26 (10.78)

12.99 (12.24)

0.368

Mitochondrial ATP production (OCR, pmol/min)

48.53 (27.69)

44.51 (26.07)

0.034

Mitochondrial maximal respiration (OCR, pmol/min)

91.86 (56.41)

86.87 (56.08)

0.226

Mitochondrial spare respiratory capacity (OCR, pmol/min)

34.81 (30.04)

31.71 (28.45)

0.147

Mitochondrial oxidative stress parameters

Log Mitochondrial oxidative stress/mass ratio

āˆ’ā€‰0.96 (0.21)

āˆ’ā€‰0.92 (0.24)

0.049

  1. Data are presented as mean (standard deviation) and are compared between normal and MCI participants by Studentā€™s t-test.Ā Bold values represent a statistical significance.
  2. ATP adenosine triphosphate, OCR oxygen consumption rate.
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