Table 1 Top-20 proteins of the eight informative centrality indices.
No | Degree | Betwenness | Closeness | Radiality | Stress | EPC | DMNC | Clustering coefficient |
|---|---|---|---|---|---|---|---|---|
1 | AKT1 | AKT1 | AKT1 | AKT1 | AKT1 | ALB | MAPKAP1 | GSX1 |
2 | TP53 | TP53 | TP53 | TP53 | PIK3CA | AKT1 | IL1A | PTTG1IP |
3 | GAPDH | SRC | GAPDH | GAPDH | IL6 | GAPDH | CASP9 | ERRFI1 |
4 | PIK3CA | PIK3CA | PIK3CA | PIK3CA | ALB | PIK3CA | XIAP | CAMP |
5 | ALB | ALB | ALB | ALB | SRC | JUN | CAMP | FOXE1 |
6 | SRC | IL6 | SRC | SRC | TP53 | TP53 | PARP1 | PDK1 |
7 | IL6 | MAPK1 | IL6 | IL6 | MAPK1 | MAPK3 | BCL2L1 | MAFA |
8 | MAPK1 | TNF | MAPK1 | MAPK1 | TNF | PIK3CB | WEE1 | SLA |
9 | MAPK3 | EGFR | MAPK3 | MAPK3 | JAK2 | IL6 | CHEK1 | DAPP1 |
10 | JUN | EGF | JUN | JUN | PIK3CD | PIK3CG | FGF1 | MAPKAP1 |
11 | PIK3CG | GAPDH | PIK3CG | PIK3CG | PIK3CB | PIK3CD | MMP2 | SLC5A5 |
12 | PIK3CD | MAPK3 | PIK3CD | PIK3CD | EGF | MAPK1 | RPS6KA1 | APEX1 |
13 | TNF | JUN | TNF | TNF | MAPK3 | MYC | HIF1A | NKX2-1 |
14 | PIK3CB | VEGFA | PIK3CB | PIK3CB | EGFR | SRC | PPARG | IL1A |
15 | EGF | PIK3CD | EGF | EGF | PIK3CG | EGFR | DAPP1 | HES1 |
16 | EGFR | JAK2 | EGFR | EGFR | GAPDH | INS | EGR1 | TSHB |
17 | MYC | PIK3CB | MYC | MYC | VEGFA | TNF | CDC25A | CDC25B |
18 | VEGFA | PIK3CG | VEGFA | VEGFA | JUN | EGF | EIF4EBP1 | THRB |
19 | INS | MYC | INS | INS | IL2 | MAPK8 | MDM2 | WEE1 |
20 | MAPK8 | INS | MAPK8 | MAPK8 | TGFB1 | HRAS | CDC25C | UBTF |
