Table 4 KEGG pathways and matched member genes.
Pathway/ID | Pathway description | Gene count | False discovery rate | Matching proteins in our network (labels) |
|---|---|---|---|---|
5200 | Pathways in cancer | 15 | 4.07E−17 | AKT2,BCL2L1,CASP8,CDKN1A,CRK,E2F2,FADD,FGF2,FGFR3, FZD3,LAMC1,PIK3R3,PLCG2,RELA,WNT5A |
4151 | PI3K-Akt signaling pathway | 15 | 4.25E−17 | AKT2,BCL2L1,CCND2,CDKN1A,FGF2,FGFR3,GNB5,IFNAR2,IRS1, LAMC1,PIK3R3,PPP2R1B,RELA |
4014 | Ras signaling pathway | 9 | 1.77E−09 | AKT2,BCL2L1,FGF2,FGFR3,GNB5,PAK1,PIK3R3,PLCG2,RELA |
4210 | Apoptosis | 7 | 1.77E−09 | AKT2,BCL2L1,CASP8,CFLAR,FADD,PIK3R3,RELA |
4390 | Hippo signaling pathway | 7 | 4.85E−08 | CCND2,FZD3,PPP2R1B,TEAD1,WNT5A |
4012 | ErbB signaling pathway | 6 | 5.99E−08 | AKT2,CDKN1A,CRK,PAK1,PIK3R3,PLCG2 |
4510 | Focal adhesion | 7 | 2.61E−07 | AKT2,CCND2,CRK,LAMC1,PAK1,PIK3R3,VCL |
5215 | Prostate cancer | 5 | 1.97E−06 | AKT2,CDKN1A,E2F2,PIK3R3,RELA |
4068 | FoxO signaling pathway | 5 | 9.19E−06 | AKT2,CCND2,CDKN1A,IRS1,PIK3R3 |
4110 | Cell cycle | 5 | 9.27E−06 | CCND2,CDKN1A,E2F2 |
4010 | MAPK signaling pathway | 6 | 1.50E−05 | AKT2,CRK,FGF2,FGFR3,PAK1,RELA |
4630 | Jak-STAT signaling pathway | 5 | 2.48E−05 | AKT2,BCL2L1,CCND2,IFNAR2,PIK3R3 |
4910 | Insulin signaling pathway | 4 | 0.000261 | AKT2,CRK,IRS1,PIK3R3 |
4310 | Wnt signaling pathway | 4 | 0.00028 | CCND2,FZD3,GPC4,WNT5A |
4150 | mTOR signaling pathway | 3 | 0.000505 | AKT2,IRS1,PIK3R3 |
4115 | p53 signaling pathway | 3 | 0.000646 | CASP8,CCND2,CDKN1A |
