Table 5 GO pathways and matched member genes.

From: Integrative microRNA and gene expression analysis identifies new epigenetically regulated microRNAs mediating taxane resistance in ovarian cancer

Pathway ID

Pathway description

Gene count

False discovery rate

Matching proteins in your network (labels)

0007165

Signal transduction

24

1.72E−07

BCL2L1,CASP8,CDKN1A,CFLAR,CRK,CSNK1E,E2F2, FADD,FGF2,FZD3,GNB5,GPC4,IFNAR2,IRS1,PAK1, PIK3R3,PLCG2,PVRL1,RELA,RUNX2,TEAD1,WNT5A

0050776

Regulation of immune response

12

5.70E−07

CASP8,CDKN1A,CRK,FADD,FGF2,FGFR3,IFNAR2, IRS1,PAK1,PLCG2,RELA,WNT5A

0043549

Regulation of kinase activity

11

2.04E−06

APC,CCND2,CDKN1A,CRK,FGF2,FGFR3,IRS1,PAK1, PIK3R3,WNT5A

0097190

Apoptotic signaling pathway

8

8.93E−06

BCL2L1,CASP8,CFLAR,E2F2,FADD,FGFR3

0010941

Regulation of cell death

13

1.10E−05

AKT2,BCL2L1,CDKN1A,CFLAR,FGF2,FGFR3,FZD3, PAK1,PLCG2,PPP2R1B,RELA

0008286

Insulin receptor signaling pathway

6

2.41E−05

AKT2,CRK,FGF2,FGFR3,IRS1,PIK3R3

0006915

Apoptotic process

11

2.89E−05

AKT2,APC,CASP8,CFLAR,E2F2,FADD,FGFR3,PAK1, PPP2R1B

0043066

Negative regulation of apoptotic process

10

3.29E−05

AKT2,APC,BCL2L1,CASP8,CDKN1A,CFLAR,FADD, FZD3,RELA,WNT5A

0043551

Regulation of phosphatidylinositol 3-kinase activity

4

4.91E−05

FGF2,FGFR3,IRS1,PIK3R3

0008284

Positive regulation of cell proliferation

9

0.000156

BCL2L1,CDKN1A,FADD,FGF2,FZD3,IRS1,LAMC1, RELA,RUNX2

0030335

Positive regulation of cell migration

6

0.000777

AKT2,APC,FADD,FGF2,IRS1,WNT5A