Table 4 Univariate and multivariate logistic regression of the clinical model and combined model for the TN subtype of breast cancer.
Feature | TN | Non-TN | Univariate analysis | Multivariate analysis | With radiomics signature | |||
|---|---|---|---|---|---|---|---|---|
P value | Odds ratio | P value | Odds ratio | P value | Odds ratio | |||
Age | 54.08 ± 10.48 | 54.18 ± 9.870 | 0.954 | 0.999 (0.965, 1.034) | ||||
Size | 33.98 ± 17.45 | 33.35 ± 19.07 | 0.844 | 1.002 (0.983, 1.020) | ||||
Breast composition | ||||||||
Dense Fatty | 40 10 | 71 29 | Ref 0.239 | 1 0.612 (0.260, 1.351) | ||||
Gross feature | ||||||||
Mass only Mass + calcification Calcification only | 29 21 0 | 46 47 7 | Ref 0.330 0.986 | 1 0.709 (0.351, 1.413) NA | ||||
Shape | ||||||||
Oval Round Irregular | 3 17 30 | 4 12 77 | 0.409 0.003 Ref | 1.925 (0.362, 9.235) 3.636 (1.567, 8.696) 1 | 0.016 | 3.028 (1.233, 7.681) | 0.335 | 1.695 (0.575, 4.998) |
Mass margin | ||||||||
Obscured Microlobulated Indistinct Spiculated | 10 7 28 5 | 18 9 50 16 | 0.986 0.555 Ref 0.301 | 0.992 (0.393, 2.414) 1.389 (0.452, 4.134) 1 0.558 (0.168, 1.598) | ||||
Mass density | ||||||||
Low Equal High | 3 23 24 | 7 61 24 | 0.861 Ref 0.013 | 1.137 (0.230, 4.478) 1 2.546 (1.223, 5.372) | 0.018 | 2.542 (1.180, 5.573) | 0.370 | 1.525 (0.598, 3.834) |
Architectural distortion | 5 | 25 | 0.036 | 0.333 (0.107, 0.869) | 0.107 | 0.403 (0.121, 1.143) | 0.419 | 0.575 (0.138, 2.084) |
Calcification morphology | ||||||||
Benign Amorphous Coarse heterogeneous Fine pleomorphic Fine linear branching | 1 2 3 11 4 | 1 2 5 33 14 | 0.451 0.300 0.468 Ref 0.817 | 3.000 (0.112, 80.288) 3.000 (0.329, 27.556) 1.800 (0.327, 8.635) 1 0.857 (0.209, 3.009) | ||||
Calcification distribution | ||||||||
Diffuse Regional Grouped Linear Segmental | 0 2 4 1 14 | 1 2 13 0 39 | 0.992 0.328 0.813 0.991 Ref | NA 2.786 (0.310, 25.086) 0.857 (0.214, 2.907) NA 1 | ||||
Radiomics signature | < 0.001 | 1781 (190, 23,225) | < 0.001 | 828 (78, 12,147) | ||||
