Table 2 Cytotoxicity of the compounds 18 isolated from Z. ajax Hort. and ellipticine (as a positive control).

From: Flavonoids and alkaloids from the rhizomes of Zephyranthes ajax Hort. and their cytotoxicity

Compound

IC50 (µM) ± SD

HepG2

SK-LU-1

KB

SW480

AGS

1

 > 100

 > 100

N.T.

N.T.

N.T.

2

 > 100

 > 100

N.T.

N.T.

N.T.

3

 > 100

 > 100

N.T.

N.T.

N.T.

4

 > 100

 > 100

N.T.

N.T.

N.T.

5

 > 100

 > 100

N.T.

N.T.

N.T.

6

 > 100

 > 100

N.T.

N.T.

N.T.

7

 > 100

 > 100

N.T.

N.T.

N.T.

8

9.7 ± 0.7

5.4 ± 0.2

11.3 ± 0.9

4.4 ± 0.1

6.5 ± 0.7

Ellipticine

1.5 ± 0.1

1.6 ± 0.1

1.5 ± 0.1

1.5 ± 0.1

0.7 ± 0.1

  1. N.T. the compounds were not tested.