Figure 2 | Scientific Reports

Figure 2

From: Betaine inhibits Toll-like receptor 4 responses and restores intestinal microbiota in acute liver failure mice

Figure 2

Effect of betaine on the TLR4/MyD88 pathway, (ZO)-1 and occludin mRNA levels and intestinal permeability in ALF mice and LPS-stimulated IEC-18 cells. (A) Intestinal permeability in each animal group. (B) The TEER value in different cell groups. (C,D) The mRNA levels of TLR4, MyD88, (ZO)-1 and occludin in different animal groups. (E,F) The mRNA levels of TLR4, MyD88, (ZO)-1 and occludin in different cell groups. #P < 0.05, compared with the normal group; *P < 0.05, compared with the model group; &P < 0.05, compared with the low-dose betaine group; ※P < 0.05, compared with the medium-dose betaine group.

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