Table 2 Correlations between the baseline characteristics and pathological findings.

From: The ISN/RPS 2016 classification predicts renal prognosis in patients with first-onset class III/IV lupus nephritis

 

eGFR, ml/min/1.73 m2

Urinary protein†, g/day or g/gCr

Haematuria*

Anti-dsDNA antibody level††, IU/ml

Serum C3 level, mg/dl

Activity index

− 0.40

0.36

0.40

0.35

− 0.21

Endocapillary hypercellularity

− 0.09

0.37

0.33

0.30

− 0.43

Neutrophils/karyorrhexis

− 0.06

0.21

0.33

0.28

− 0.20

Hyaline deposits

− 0.17

0.19

0.26

0.32

− 0.31

Fibrinoid necrosis

− 0.03

0.07

0.06

0.16

− 0.04

Cellular/fibrocellular crescents

− 0.34

0.24

0.27

0.19

− 0.03

Interstitial Inflammation

− 0.55

0.15

0.14

0.05

0.13

Chronicity index

− 0.52

0.11

0.07

0.05

0.19

Global/segmental sclerosis

− 0.26

− 0.02

0.00

− 0.05

0.17

Fibrous crescents

− 0.06

− 0.06

− 0.06

0.07

0.07

Interstitial fibrosis

− 0.56

0.17

0.10

0.05

0.18

Tubular atrophy

− 0.53

0.13

0.08

0.06

0.16

  1. Correlations between the baseline clinical data and pathological scores are described by using Spearman correlation coefficients.
  2. eGFR estimated glomerular filtration rate.
  3. Number of missing data: †N = 1, ††N = 27.
  4. *Divided into four categorical variables depending on the severity; − (0), + (1), ++ (2), +++ (3).
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