Figure 1
From: Genes associated with cognitive performance in the Morris water maze: an RNA-seq study
MWM cognitive performance. (a) Experimental design. (b) The correlation among the parameters of the MWM test among all the mice. (c) Hierarchical clustering of samples based on the number of successful attempts to find the platform and the average latency to find the platform in the MWM test. Mice were subdivided into three groups: low (LP), medium (MP), and high (HP) MWM performance. Hippocampus samples from the mice labeled as LP or HP were used in the subsequent transcriptome analysis. (d) The learning curve in the MWM test shows the change in latency to find the platform during 16 training trials (four trials a day for 4 days) in groups LP, MP, and HP. (e) Scatter plots showing the distribution of numbers of successful attempts to find the hidden platform and the distribution of latency times to find the platform among the animals. (f) A comparison of parameters of the MWM test between groups LP and HP. Data are presented as mean ± SEM (d,f), *p < 0.05, **p < 0.01, ***p < 0.001 as compared with the LP group, ###p < 0.001 as compared with the Target sector.
