Figure 4
From: Dynamic data-driven meta-analysis for prioritisation of host genes implicated in COVID-19
Cellular functions of the 100 highest ranked genes in the MAIC output. Protein products of these genes have diverse cellular locations and are associated with numerous processes relevant to the viral life cycle and host immune system. Stages of the betacoronavirus life cycle: (1) S protein-mediated attachment to the cell surface. (2) Endocytosis. (3) Membrane fusion and viral genome release into the cytoplasm. (4) Assembly of the replication-transcription complex, translation of mRNA. (5) Viral replication and virion assembly. (6) Virion maturation, budding and translocation of vesicles.
