Table 1 In vitro antiplasmodial activity of EHT1864 and 1A116.

From: Characterization of the erythrocyte GTPase Rac1 in relation to Plasmodium falciparum invasion

 

D10 IC50a (nM)

W2 IC50a (nM)

EHT1864

3877 ± 738

7748 ± 1821

1A116

3209 ± 1173

6888 ± 1407

Chloroquine

16 ± 3

418 ± 75

  1. aThe results are expressed as IC50 ± SD of at least three independent experiments each performed in duplicate.