Table 1 Baseline characteristics of subjects.

From: DNA damage in human glomerular endothelial cells induces nodular glomerulosclerosis via an ATR and ANXA2 pathway

 

All subjects

Nodular lesion (+)

Nodular lesion (−)

p values

N = 30

N = 14

N = 16

(+) vs. (−)

Gender (male, %)

20 (66.7)

11 (78.6)

9 (56.2)

0.04

Age (years old)

54.3 ± 18.9

55.9 ± 14.8

52.9 ± 22.2

0.67

Blood pressure (mmHg)

Systolic

129.4 ± 19.2

133.8 ± 18.2

125.6 ± 19.8

0.25

Diastolic

71.1 ± 11.0

75.9 ± 9.2

66.9 ± 11.0

0.22

Urinary protein (g/gCr)

3.6 ± 3.9

4.2 ± 4.2

3.1 ± 3.6

0.40

Serum creatinine (mg/dL)

1.22 ± 0.58

1.37 ± 0.48

1.10 ± 0.65

0.22

HbA1c (%)

6.1 ± 1.1

6.4 ± 1.4

5.8 ± 0.8

0.16

Diabetes mellitus

8

3

5

N.S.

Nephrosclerosis

6

3

3

Transplanted allografts

11

6

5

Minor glomerular abnormality

5

0

5

  1. The population included 30 patients with or without nodular lesions.
  2. Values are means ± SD, N.S., not significant.
  3. Comparisons between groups were evaluated by the Mann–Whitney U test.
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