Table 3 Factors that influenced changes in Collagen type 6.

From: DNA damage in human glomerular endothelial cells induces nodular glomerulosclerosis via an ATR and ANXA2 pathway

Objective variable:

COL6-positive area

Standardization β

t

Significance**

γ-H2AX (%)

0.539

2.668

0.014

Average blood pressure (mmHg)

0.005

0.022

0.982

Diabetes mellitus

(+) = 1, (−) = 0 *

 −0.256

 −1.273

0.216

uPCR (g/gCr)

 −0.494

–2.184

0.039

sCr (mg/dL)

0.065

0.313

0.757

Age (year)

0.37

1.855

0.076

  1. Abbreviations: COL6; Collagen type 6, γ-H2AX; Histone H2AX phosphorylation on Serine 139, sCr; serum creatinine levels. Mean blood pressure was calculated as (systolic blood pressure-diastolic blood pressure)/3 + diastolic blood pressure.
  2. *Subjects with diabetes mellitus (DM) were classified as 1 and non-DM subjects as 0.
  3. **Factors were analyzed by a linear multiple regression analysis.
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