Table 1 Variants with strong signatures of selection in coding genomic regions sorted by ihs scores from most negative (top) through least negative to most positive (bottom).

rs10947368

6:32975341

C

T

− 6.422

5.73e−05

K120N

HLA-DOA

rs8192564

6:32191822

G

A

− 5.494

0.0024

–

NOTCH4

rs115261305

6:32793668

C

A

− 5.385

0.0030

–

TAP2

rs1126544

6:33037061

G

C

− 5.133

0.0085

T121T

HLA-DPA1

rs3800326

6:28264717

C

T

− 5.111

0.0089

P256L

PGBD1

rs61737338

6:28227217

C

T

− 4.922

0.0154

S23F

NKAPL

rs7943508

11:57003581

C

T

− 4.861

0.0176

V300I

APLNR

rs6582601

12:38716034

C

T

− 4.850

0.0183

–

ALG10B

rs2233954

6:31105672

G

A

− 4.802

0.0207

–

PSORS1C2

rs34304311

6:28093263

G

A

− 4.657

0.0298

L14L

ZSCAN16

rs6115256

20:25666642

C

T

− 4.600

0.0348

L48L

ZNF337

rs17190762

6:31126992

G

A

− 4.528

0.0429

–

TCF19

rs10896290

11:56128081

A

G

− 4.524

0.0429

Y120C

OR8J1

rs61729683

6:32185818

C

T

− 4.522

0.0430

A526A

NOTCH4

rs78133850

11:57004659

G

A

− 4.508

0.0442

–

APLNR

rs73468666

11:56958933

G

A

− 4.493

0.0462

–

LRRC55

rs75301276

11:55944198

C

T

− 4.491

0.0462

Y35Y

OR5J2

rs58567530

16:48172185

C

A

− 4.489

0.0464

L311L

ABCC12

rs3013106

1:13802437

G

A

4.995

0.0116

S254S

LRRC38