Table 2 Association of OCLN, CLDN3, CLDN, DSG3 and TSLP expression with demographical parameters of AR patients (n = 30).

From: Reduced occludin and claudin-7 expression is associated with urban locations and exposure to second-hand smoke in allergic rhinitis patients

 

n (%)

OCLN expression

CLDN3 expression

CLDN7 expression

DSG3 expression

TSLP expression

 < Median

 ≥ Median

p-value

 < Median

 ≥ Median

p-value

 < Median

 ≥ Median

p-value

 < Median

 ≥ Median

p-value

 < Median

 ≥ Median

p-value

Age (years)

Median (range)

30 (20–54)

 

 < 27.5

15 (50.0)

7 (23.3)

8 (26.7)

1.000

8 (26.7)

7 (23.3)

0.715

7 (23.3)

8 (26.7)

0.712

10 (33.3)

5 (16.7)

0.028

8 (26.7)

7 (23.3)

0.464

 ≥ 27.5

15 (50.0)

7 (23.3)

8 (26.7)

7 (23.3)

8 (26.7)

6 (20.0)

9 (30.0)

4 (13.3)

11 (36.7)

6 (20.0)

9 (30.0)

BMI

Median (range)

30 (19.0–34.02)

 

 < 26.5

15 (50.0)

11 (36.7)

4 (13.3)

0.003

8 (26.7)

7 (23.3)

0.715

7 (23.3)

8 (26.7)

0.712

8 (26.7)

7 (23.3)

0.464

7 (23.3)

8 (26.7)

1.000

 ≥ 26.5

15 (50.0)

3 (10.0)

12 (40.0)

7 (23.3)

8 (26.7)

6 (20.0)

9 (30.0)

6 (20.0)

9 (30.0)

7 (23.3)

8 (26.7)

Sex

Male

10 (33.3)

4 (13.3)

6 (20.0)

0.709 (F)

4 (13.3)

6 (20.0)

0.434

5 (16.7)

5 (16.7)

0.705 (F)

5 (16.7)

5 (16.7)

1.000 (F)

6 (20.0)

4 (13.3)

0.442 (F)

Female

20 (66.7)

10(33.3)

10 (33.3)

11 (36.7)

9 (30.0)

8 (26.7)

12 (40.0)

9 (30.0)

11 (36.7)

8 (26.7)

12 (40.0)

Exposure to secondhand smoke

Yes

21 (70.0)

8 (26.7)

13 (43.3)

0.236 (F)

9 (30.0)

12 (40.0)

0.427 (F)

12 (40.0)

9 (30.0)

0.042 (F)

10 (33.3)

11 (36.7)

1.000 (F)

12 (40.0)

9 (30.0)

0.118 (F)

No

9 (30.0)

6 (20.0)

3 (10.0)

6 (20.0)

3 (10.0)

1 (3.3)

8 (26.7)

4 (13.3)

5 (16.7)

2 (6.7)

7 (23.3)

Home location

Urban

16 (53.3)

11 (36.7)

5 (16.7)

0.010

9 (30.0)

7 (23.3)

0.464

6 (20.0)

10 (33.3)

0.491

7 (23.3)

9 (30.0)

0.732

10 (33.3)

6 (20.0)

0.063

Rural

14 (46.7)

3 (10.0)

11 (36.7)

6 (20.0)

8 (26.7)

7 (23.3)

7 (23.3)

7 (23.3)

7 (23.3)

4 (13.3)

10 (33.3)

Having pets

Yes

17 (56.7)

8 (26.7)

9 (30.0)

0.964

8 (26.7)

9 (30.0)

0.712

5 (16.6)

12 (40.0)

0.078

10 (33.3)

7 (23.3)

0.127

10 (33.3)

7 (23.3)

0.127

No

13 (43.3)

6 (20.0)

7 (23.3)

7 (23.3)

6 (20.0)

8 (26.7)

5 (16.7)

4 (13.3)

9 (30.0)

4 (13.3)

9 (30.0)

Frequency of changing bedsheet

Weekly

12 (40.0)

6 (20.0)

6 (20.0)

0.363 (F)

5 (16.7)

7 (23.3)

0.877 (F)

4 (13.3)

8 (26.7)

0.414 (F)

5 (16.7)

7 (23.3)

0.686 (F)

5 (16.7)

7 (23.3)

0.686 (F)

Monthly

14 (46.7)

5 (16.7)

9 (30.0)

8 (26.7)

6 (20.0)

8 (26.7)

6 (20.0)

8 (26.7)

6 (20.0)

8 (26.7)

6 (20.0)

2-Monthly

4 (13.3)

3 (10.0)

1 (3.3)

2 (6.7)

2 (6.7)

1 (3.3)

3 (10.0)

1 (3.3)

3 (10.0)

1 (3.3)

3 (10.0)

Frequency of housekeeping

Daily

11 (36.7)

5 (16.7)

6 (20.0)

0.095 (F)

4 (13.3)

7 (23.3)

0.642 (F)

5 (16.7)

6 (20.0)

1.000 (F)

5 (16.7)

6 (20.0)

0.468 (F)

5 (16.7)

6 (20.0)

0.468 (F)

Weekly

12(40.0)

8 (26.7)

4 (13.3)

7 (23.3)

5 (16.7)

5 (16.7)

7 (23.3)

7 (23.3)

5 (16.7)

7 (23.3)

5 (16.7)

Alternate day

7 (23.3)

1(3.3)

6 (20.0)

4 (13.3)

3 (10.0)

3 (10.0)

4 (13.3)

2 (6.7)

5 (16.7)

2 (6.7)

5 (16.7)

  1. p < 0.05 shown in bold. Abbreviation: AR, allergic rhinitis; OCLN, occludin; CLDN3, claudin-3; CLDN7, claudin-7; DSG3, desmoglein 3; TSLP, thymic stromal lymphopoietin; BMI, body mass index.
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