Figure 4
Perturbation of serum amino acid profile reverses arginine deficient diet-induced lipid accumulation in the liver. (a–c) Six-week-old male Wistar rats were fed the CN diet, ΔArg diet, both arginine and methionine deficient diet (ΔArg/ΔMet) (a), both arginine and BCAAs deficient diet (ΔArg/ΔBCAA) (b), or both arginine and histidine deficient diet (ΔArg/ΔHis) (c) for seven days. TAG levels in their livers. (d) Serum amino acid concentrations of rats shown in (a–c) were measured. Data of serum amino acid concentration are shown as a fold of the mean value of the CN group (dotted line), and average values of each experimental diet group (continuous line) are indicated. [bar; means ± S.E.M., (n = 4), Tukey–Kramer test].
