Table 2 Factors associated with DFS and OS in the studied population.

From: Activation of T helper cells in sentinel node predicts poor prognosis in oral squamous cell carcinoma

Factor

No. of patients

No. of relapses

No. of deaths

Mean DFS (95% CI)

DFS (%)

DFS p-value

Mean OS (95% CI)

OS (%)

OS p-value

aOR for relapse (95% CI)

P-value

Age

 < 62

6

0

0

100.0

0.084

100.0

0.246

 

 ≥ 62

10

4

2

60.0

80.0

Gender

Female

11

4

2

63.6

0.116

81.8

0.300

 

Male

5

0

0

100.0

100.0

pT status

T0

8

2

0

37.2 (28.8–45.7)

75.0

0.973

100.0

0.173

 

T + 

8

2

2

33.6 (23.5–43.7)

75.0

75.0

pN status

N0

15

4

2

73.3

0.550

86.7

0.699

 

N + 

1

0

0

100.0

100.0

Brandwein scale

Low risk

1

1

0

33.0 (33.0–33.0)

0.0

0.508

100.0

0.660

 

Intermidiate risk

4

1

0

27.8 (17.1–38.4)

75.0

100.0

High risk

10

2

2

36.9 (28.5–42.9)

80.0

80.0

CD4+ CD69+ in sentinel node

 ≤ 37.5 (low)

7

3

2

19.7 (12.6–26.9)

57.1

0.033

71.4

0.064

Ref

0.295

 > 37.5 (high)

9

1

0

42.6 (40.1–45.1)

88.9

100.0

0.004 (0.00–119.70)

CD8+ CDHLA-DR+ in sentinel node

 < 25.2 (low)

8

0

0

100.0

0.045

100.0

0.141

Ref

0.248

 ≥ 25.2 (high)

8

4

2

50.0

75.0

136.5 (0.033–569,208.6)

  1. Univariate analysis of DFS and OS with p value determined by log-rank test.
  2. Multivariate analysis by Cox proportional-hazards model for factors significant in univariate analysis.