Figure 2
From: The role of the PIK3CA gene in the development and aging of the brain

Pik3ca+/− mice have substantially reduced brain weight and size. (A) Brain weight of mice at different ages. Data represents mean ± SD (n = 3–16). **P < 0.01, ***P < 0.001 (B) H&E staining in the indicated mice. Upper panel (coronal section), > 22 months old. Scale bar, 2 mm. bottom panel (sagittal section), 12 months old, scale bar, 5 mm.